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Antiviral creams containing aciclovir are widely available

It is important that pregnant women who smoke are identified and referred for specialist support at the earliest opportunity

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In our study, we focused on the moist STPs because high moisture content plays a significant role in the increased level of TSNAs by facilitating the growth of the microorganisms ( in vitro assay using epithelial cells (AMOL-III) from the oral leukoplakia of a Khaini user and treatment with aqueous extract of Khaini showed alteration in the expression of proteins involved in cell cycle regulation and DNA methylation, suggesting the role of Khaini in oral carcinogenesis (Rohatgi et al., 2005)