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Brands such as Obagi, Cosmelan and Dr Sylvia Advanced Clear Skin Program are among the known safe and effective lightening products that include prescription strength 4% hydroquinone to treat pigmentation and other spots in the skin

Rauwolscine, also known as Alpha-Yohimbine, is a rare close cousin of Yohimbine that stays active in your body longer and is stronger at blocking those same fat-storing receptors

Cell culture SH-SY5Y cells were grown in Dulbeccos Modified Eagles Medium (DMEM) supplemented with 10% heat-inactivated fetal bovine serum and cultured at 37 C under humidified 5% CO 2 atmosphere