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[3] GSTs are essential in this process because they catalyze the nucleophilic attack of glutathione on various electrophilic residues of xenobiotic substrates, thereby preventing their disruption of vital cellular proteins and nucleic acids

GHK-Cu modulates expression of over 4,000 genes through copper-dependent pathways, including collagen synthesis, metalloproteinase regulation, and antioxidant defense

May 2007;38(4):456-9