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Lead, cadmium (from smoking) and arsenic disturb dopamine, this neurotransmitter gives the brain energy, motivation and the capacity for pleasure, when it becomes deficient you can get a low energy demotivated depression

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Neuroprotective function of high glycolytic activity in astrocytes: common roles in stroke and neurodegenerative diseases

Neurological and Cognitive Pathways Thymosin-derived peptides are under investigation for their potential to influence neural recovery and maintenance of central nervous system integrity