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extract following intraperitoneal administration with a lethal dose of APAP was found to be protective against APAP-induced necrosis by downregulating the cytochrome P450 CYP2E1 protein levels in vitro (Hau et al., 2009)

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An animal is considered to be in the open area when all four paws are in an open quadrant and in the closed area only when all four paws have crossed from the open to the closed boundary

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