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Downregulation of glutathione biosynthesis contributes to oxidative stress and liver dysfunction in acute kidney injury

BPC-157 is a synthetic peptide derived from a protective protein found naturally in gastric juice

Targeting 25HC, alone or in combination with anti-PD-1 immunotherapy, has been shown to improve the efficacy of immunotherapy by reprogramming the tumor microenvironment and reducing immunosuppression (84)

In vitro studies using endothelial cell cultures have shown that BPC-157 exposure leads to increased VEGF receptor expression and enhanced formation of capillary-like structures in Matrigel assays