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South Florida patients, particularly those in the Fitzpatrick III through VI range who have higher baseline melanin activity and different wound healing patterns, sometimes see post-inflammatory hyperpigmentation respond more slowly than texture or firmness

Previous in vitro research has revealed that supplementation of GSH at a concentration of 5 mM to H

These processes not only compromise cellular bioenergetics but also trigger immune responses through sensors such as cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING), or activate NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasomes, leading to secretion of proinflammatory cytokines such as interleukin (IL)-1 (Mills et al., 2017)