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Also, individuals who have undergone certain surgical procedures, including intestinal resection, bypass, or bariatric surgery, which may reduce Vitamin B12 absorption, are also eligible

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In-vitro studies have applied this compound in the context of enzymatic regulation and biochemical signalling, with particular attention to NNMT's reported role in metabolic tissue biology

However, it is essential to realize that there is also a disorder called vitamin B12-responsive neuropathy