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It antagonizes haloperidol-induced behavioural supersensitivity to amphetamine which, results in dopaminergic neurotoxicity and nigrostriatum damage due to increased lipid peroxidation

The studies were done on rodents, the b12 isnt available in the kidneys for very long, weeks, not months it seems.and whether humans with b12 deficiency because of a broken system can access this b12 we wont know without further research