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Journal of Neural Transmission Suppl 72, 57-67Google Scholar 151Burton, N.C., Kensler, T.W

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Morphologically, ferroptosis is characterized by necrotic-like features, including loss of mitochondrial cristae, increased membrane density, outer membrane rupture, and reduced mitochondrial volume, while preserving plasma membrane integrity during early stages and maintaining normal nuclear morphology

For patients diagnosed with acute PACG, oral administration of deferiprone has been observed to traverse the BRB and chelate abnormally elevated Fe 2+ in the retina following ph-IOP, which contributed to the prevention of RGC ferroptosis and the preservation of visual acuity (95)