glutathione ms Simultaneous quantitation of oxidized and reduced via LC-MS/MS: An insight into the redox state of hematopoietic stem cells Quantification of glutathione and cysteine

doi: 10.1042/bst0370329 251

It requires selenium as a cofactor and contains a selenocysteine amino acid residue in the active site of each monomer that participates in the actual mechanism of the enzyme

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Considering the importance of cellular redox status, dysregulation in the redox status by GSH under pathological conditions would be involved in some human diseases such as hemolytic anemia, human immunodeficiency virus infection/acquired immune deficiency syndrome, liver disease, and cystic fibrosis [50]