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131 The system, termed LNC-Ted HAKPV, offered three principal therapeutic benefits: (1) promotion of endogenous GLP-2 production to enhance intestinal growth and repair, (2) targeted anti-inflammatory action mediated through HA-KPV's modulation of the CD44/TLR4 pathways, and (3) redox-responsive release of the anti-inflammatory tripeptide KPV via disulfide bonds, activated under inflamed intestinal conditions

The only effective therapy is supplementing thiamine

They are also potential candidates for peptidomimetics for studying protein-protein, protein-peptide, and peptide-peptide interactions

In rodent studies, animals with greater GLUT4 expression display heightened insulin sensitivity, whereas those with reduced GLUT4 levels demonstrate impaired insulin signaling