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If signaling is off, scars can become raised, depressed, or discolored

however, theoretical risks include off-target activation of the HGF/c-Met pathway, which is implicated in oncogenesis, warranting caution regarding long-term use

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Although brain infarction volume reduction did not reach statistical significance, motor performance in the rotarod test significantly recovered in DSIP-treated animals compared to vehicle controls confirming a functionally relevant neuroprotective effect at the behavioural level and establishing intranasal delivery as a viable route for CNS DSIP research