When MSM, alone or in combination with Vit C, was administered, a reduction in CO release was found
As the main transcription factor of Th17 cell, RORt collaborates with other transcription factors, such as ROR, IRF4, and Runx1, to synergistically stimulate Th17 cell growth and IL-17 release ( Foxp3 interacts with several transcription factors, such as STAT5, NFAT, and BACH2, to influence the Treg cells' development, stability, and epigenetic modifications
Statistics and reproducibility Statistical significance was determined using independent t -test for immunohistochemical and western blot analyses, and one-way analysis of variance for cell cycle and apoptosis detection by GraphPad Prism 7.0 software (GraphPad, Inc., La Jolla, CA, USA)
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