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The disadvantage of administering enzymatic antioxidants to humans however is (1) the possibility of allergic reactions (in the case of a bacterial or fungal derived enzyme) of varying degrees of severity

You might be at higher risk of developing a histamine intolerance if you have a GI disorder, such as: Functional dyspepsia Irritable bowel syndrome (IBS) Irritable bowel disease (IBD), such as ulcerative colitis or Crohns disease Celiac disease Food allergies Malabsorption Small intestinal bacterial overgrowth Colon polyps There you have it

This holds true even when people are in a calorie deficit or trying to lose weight

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