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Specifically, the leakage of electrons from mitochondrial ETC complexes gives rise to ROS, which can subsequently react with ferrous ions (Fe 2+ ) to generate OH radicals [89]

Side effects are not common but may include: Mild gastrointestinal upset (especially if this is the first time supplementation has been started) Loose stools or diarrhoea at higher doses Greenish discoloration of urine (harmless - temporary) These side effects usually end themselves within a few days as the dog's system adjusts