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In a recently published review, the advantages of eryptosis over hemolysis as a toxicological endpoint have been summarized, emphasizing that eryptosis in vitro testing has a higher sensitivity, is more accurate and reproducible, provides better quality control, and can shed light on the cytotoxicity-mediating molecular mechanisms compared with hemolysis [450]

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Rapamycin and the recently developed more specific mTOR inhibitors, i.e., rapalogs, are promising therapeutic compounds in the treatment of cancers and several autoimmune and chronic inflammatory diseases [66]

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