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In conclusion, dedicating more effort and resources to establishing recommended dietary reference intakes (DRIs)/recommended dietary allowances (RDAs) for SCA patients is essential, and nutritional intervention should be included as an adjunct treatment in tandem with standard practice

When administered as a 250 mg rectal suppository, glutathione bypasses the gastrointestinal tract, potentially reducing degradation by stomach acids and enzymes, thus allowing for better absorption

Across the entire rare disease trial continuum, DHTs hold promise to support patient-centric approachesfrom trial design to patient recruitment and retention, and to data monitoring, outcome assessment, and long-term healthcare (Fig

The mortality rates in severe sepsis were almost 41% in Europe against around 28 We aim to investigate the effects of high dose l-carnitine supplementation on inflammatory mediators, oxidative stress, clinical outcomes, and the rate of mortality in ICU septic patients