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It holds the potential to elucidate the impact of cellular growth conditions such as heat-shock, starvation, or UV damage on the 20S substratome, while also uncovering differences between diverse cell types

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Typical research applications include: combined tissue-repair and remodeling models (tendon, ligament, muscle, connective tissue)

An emerging role for tocopherols and tocotrienols in response to neuroinflammation has been demonstrated and the occurrence of its positive effects on oxidative damage and Alzheimer pathology has been proposed