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Discussion We identified higher CSF-corrected frontal and sensorimotor GSH levels for older compared to younger adults when accounting for age-related cortical atrophy

The conclusion was supported by coherent epidemiologic evidence for biologically related effects (eg, memory impairment, ocular conditions, decrements in attention, cognitive function, and visuospatial performance, as well as increases in depression and anxiety and other social and emotional behavior and regulation symptoms)