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This interaction both disrupts peptidoglycan assembly in spore-forming bacilli and promotes the aggregation of nisinlipid complexes that create pores in the cytoplasmic membrane, leading to loss of membrane integrity and cell death (198, 199)

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Wound healing models: All three peptides have demonstrated accelerated wound closure in excisional, incisional, and burn models in published preclinical literature

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Topical formulations have been associated with significant improvements in hyperpigmentation and skin quality, with minimal and self-resolving side effects

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