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Others use NAD+ periodically during times of high stress, demanding work schedules, or mental fatigue

In the Hands: Which Joints Each Affects In the hands, osteoarthritis typically affects the joints closest to the fingertips (DIP) and the base of the thumb, while rheumatoid arthritis typically affects the knuckles (MCP) and middle finger joints (PIP) symmetrically on both hands

Neuromuscul Disord 2018;28:415

Conclusion: CA2-CA3 atrophy may serve as a radiological marker of tau pathology in CAA with AD-like profiles, independently of age-related changes, highlighting a continuum between these diseases