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Core signaling pathways in the regulation of melanogenesis Melanogenesis is a complex process that is modulated by a network of pivotal signaling cascades and transcription factors, which is controlled at different levels

At the same time, the clinical populations included in the studies typically consisted of a younger cohort, and hence, it may not be easy to generalize the findings to an older clinical cohort

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Clearance of damaged mitochondria by decreasing oxidative stress signals over time and increasing mitophagy physiology are necessary for limited NLRP3 activation