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Mitochondrial insufficiency in astrocytes is a hallmark of PD, leading to a profound deterioration of astrocytic homoeostatic, supportive, and protective capabilities

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In the present study, the possibility of using glutathione-S-transferase gene P1 (GST-P1), a genetic marker involved in carcinogen detoxification, antineoplastic product activation and metabolism of chemotherapeutic agents (9), in patients that are in the grey area of the PSA values was evaluated