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According to the NHS, gastric bypass remains one of the most commonly performed bariatric procedures in the UK, as it is effective for both weight loss and metabolic improvement

The human and genes are located on chromosome 8 pterq11, and share 87% coding sequence homology (Blum et al., 1990)

In addition, Losartan, an angiotensin-II type I receptor antagonist, improved hepatic fibrosis by inhibiting the activation of HSCs in mice models and is now evaluated in a phase 3 trial (NCT01051219) for NASH patients with steatohepatitis and fibrosis (Kleiner fibrosis classification F1-F3)