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HNF1 drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC)
51:e2121
In fact, recent work reveals that the Cys residues in a canonical RNA-binding CCCH ZF protein, tristetraprolin (TTP) involved in regulating inflammation, are subject to persulfidation by hydrogen sulfide (H 2 S) and molecular oxygen, which may involve the intermediacy of hydrogen disulfide radical anion and superoxide anion, followed by disulfide bond formation and zinc release
By fostering interdisciplinary collaboration across scientific, clinical, and social science disciplines, and engaging patient-facing organizations, innovative solutions can be developed to address the complex needs of women with endometriosis-associated infertility across the reproductive lifespan
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