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Rationale for targeting 7nAChR in ASD Postmortem examination of individuals with ASD has revealed abnormalities in cholinergic nuclei, cholinergic projections, cholinergic receptors, and growth factors responsible for the development and upkeep of cholinergic neurons [22]

The practical questions are: what receptor pathway does it use, what human data exists, what is the current approval status, and how does it compare with approved GLP-1 options