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Many protocols include a maintenance phase with antioxidants, barrier-friendly actives, and follow-ups to reduce recurrence

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At the end of the day, Tirzepatide titration after many more years (in trial and in real-world setting) has a more well understood titration schedule than the pre-approved CagriSema

In particular, FOXO1 regulates cell cycle progression, apoptosis, and angiogenesis 144,145 , and promoted both in vivo and in vitro wound healing by preventing oxidative stress in keratinocytes via the upregulation of GPX-2 and GADD45 thus maintaining TGF-1 mediated migration and apoptosis inhibition 146