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Description

In the endothelium, nitric oxide directly affects mitochondrial metabolism through interaction with cytochrome C, providing cytoprotection against free radicals

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Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase

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The picture is one of systems-level pharmacology rather than single-target agonism

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Both can play a role in supporting antioxidant health

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