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B12 is a water-soluble nutrient that is essential for energy production, red blood cell creation, neurological function, heart health, and DNA synthesis

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We estimate that people who are homozygous for the risk alleles at both the GLP1R and GIPR loci have a 14.8-fold increased odds (95% confidence interval [6.2, 35.8]) of tirzepatide-mediated vomiting, compared with those homozygous for the non-risk alleles

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