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After migration to the nucleus, Nrf2 undergoes heterodimeric combinations with other transcription factors, such as small Maf protein and binds to the 5-upstream cis-acting antioxidant regulatory sequence ARE or electrophile response elements (EpRE), located in the promoter region of genes encoding various antioxidant/detoxifying enzymes

This method ensures that your body gets the maximum benefit from each nutrient, helping to mitigate the effects of oxidative stress and support your natural hormone production processes