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These include members of the transient receptor potential (TRP) channel superfamily, which mediate extracellular calcium influx in response to hormonal and environmental cues, and store-operated calcium entry (SOCE) channels, such as the STIM1-ORAI1 complex, which replenish intracellular calcium stores following depletion [31]

This disorder is inherited in an autosomal recessive pattern, which means the defective gene is located on an autosome, and two copies of the gene - one from each parent - are required to be born with the disorder

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Allow the vial to sit in the refrigerator for 30 to 60 minutes before adding water