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TLX interacts with HDAC3 and HDAC5 to recruit these histone deacetylases to the promoters of cell cycle regulatory factor p21 and tumor suppressors such as pten and p53 to repress their expression ( Fig

[3] However, B 12 deficiency in the elderly is a significant concern, and is related to dementia

Its best for severe cases or when your body cant absorb B12 well

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