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Updated phase I trial of anti-LAG-3 or anti-CD137 alone and in combination with anti-PD-1 in patients with recurrent GBM

Ethics declarations Ethics approval and consent to participate We obtained institutional review board (IRB) approval from the Ethical Committee at the University Hospital Frankfurt (20549) and written informed consent was waived for this retrospective study

These observations were performed by three independent physiatrists who were blinded to the treatment groups, ensuring unbiased assessment

CagriSema is the fixed-ratio combination of cagrilintide + GLP-3 developed by Novo Nordisk as a single weekly injection for obesity