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Focus on changing mitochondrial function

Benign familial hypermobility syndrome and Trendelenburg sign in a painting "the three graces" by Peter Paul Rubens (1577-1640)

Ultimately, combining senolytics (to eliminate the source) and senomorphics (to immediately suppress the harmful output) represents a promising synergistic approach to comprehensively tackle the problem of therapy-induced senescence and its detrimental impact on the TME and treatment outcomes (Lelarge et al., 2024)

The tetrapeptide (Nle1-YIH) and tripeptide (Nle1-YI) fragments of the Nle1-AngIV analog of AngIV were previously found to be the smallest active fragments capable of overcoming scopolamine-induced cognitive dysfunction in a spatial learning task