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In addition, -HB exerts neuroprotective effects by attenuating microglial activation through stimulation of the hydroxycarboxylic acid receptor 2 (HCA2)

**NAD levels decline sharply with age**, dropping by nearly 50% between age 40 and 60

Bone & Organ Regeneration The regenerative scope extends well beyond skin: Bone: Low doses improve fracture healing, collagen deposition, and osteoblast activity