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Oncology 91(1):55-60, 2016

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204 Similarly, administration of the PRMT5 inhibitor PJ-68 in a CML mouse model with high expression of PRMT5 LSCs could deplete DVL3, thereby inhibiting Wnt/-catenin signaling and significantly prolonging the survival time of a retroviral BCR-ABL-driven CML mouse model

Inside that sealed architecture, Syntha-Pep carries three actives the manual describes as "hero molecules": bioengineered PDRN (produced by recombinant fermentation, not extracted from salmon), sh-Oligopeptide-1 (the synthetic-human form of Epidermal Growth Factor), and Copper Tripeptide-1, which is GHK-Cu