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[80] The condition is easily treatable with abstinence or lowering of kava intake, as the skin appears to be returning to its normal state within a couple of weeks of reduced or no kava use

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Formed through the non-enzymatic, free radical-mediated peroxidation of arachidonic acid, F2-IsoPs are chemically stable and specific to lipid peroxidation processes, distinguishing them from earlier markers like TBARS and malondialdehyde (MDA) (Milne et al., 2007