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Vaccaro et al., 2020)

Determine which kind of B12 is most absorbable based off of COMT and VDR SNP status Support the Long Route pathway utilizing folate or 5-methyl-THF (5-MTHF), for MTHFR mutations Customized support Rich's protocol While Yasko pioneered the methylation protocol for autism, Rich Van Konynenburg, trained as a physicist, was the first to apply the methylation protocol to CFS/ME and fibromyalgia