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The two peptides use complementary rather than identical mechanisms

A condition commonly associated with histamine intolerance is Mast Cell Activation Syndrome (MCAS), a disorder in which mast cells inappropriately and excessively release mediators, including histamine

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If approved, CagriSema would provide patients and healthcare professionals with an additional treatment option supported by results from the REDEFINE clinical program, including robust efficacy, high treatment completion rates, and a tolerability profile consistent with its underlying pharmacology