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(2021) Effectiveness of N-acetylcysteine in treating clinical symptoms of substance abuse and dependence: a meta-analysis of randomized controlled trials

[5] The researchers also note that IR and IGF1R act as identical portals to the regulation of gene expression, with differences between insulin and IGF-1 effects due to a modulation of the amplitude of the signal created by the specific ligand-receptor interaction. The IGF-1R is referred to as the physiologic receptor due to its potential higher affinity (approximately 100 times higher) for IGF-1 as compared to the insulin receptor

DOI: 10.1002/jnr.490160211 Rizzoli SO, Betz WJ (2004): The structural organization of the readily releasable pool of synaptic vesicles

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