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This means that EpCAM-specific antibodies are conjugated with cytotoxic agents, such as doxorubicin, paclitaxel, calicheamicin, topoisomerase I inhibitors, alpha amanitin, and indolinobenzodiazepine pseudodimers (IGNs), to specifically kill the EpCAM+ tumor cells

Previous research has established that ZIP4 is predominantly localized to the apical brush border of enterocytes, facilitating zinc uptake from the intestinal lumen

IP3 may trigger the release of calcium ions (Ca2+) from intracellular stores, while DAG may activate protein kinase C (PKC)

Although biotransformation reactions take place within cytoplasm and mitochondria but they mostly happen within endoplasmic reticulum (E.R)