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doi: 10.1038/sj.cdd.4401975 80 GrossAJockelJWeiMCKorsmeyerSJ

J Lipid Res 1976

Treated mice show a 15%20% increase in basal metabolic rate and elevated energy expenditure, with effects positively correlated with NNMT inhibition

331 Oxidative stress is a characteristic feature of chronic kidney disease, initiating inflammation and endothelial dysfunction, which accelerates arteriosclerosis