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Schaller, H

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Moreover, mediators can interact with the nerve terminals or ion channels in the airways to inhibit or promote depolarisation, alter the response to activating stimuli, or lead to changes in gene expression modifying the function of the sensory fibre itself (Taylor-Clark & Undem, 2006)

How long it will still show on a urine drug test is estimated based on frequency of use, but does not take into account the weight and body fat of the marijuana user: One Time User may show positive for 1-6 days Moderate User may show positive for 7-13 days Frequent User may show positive for 15 or more days Heavy User may show positive for 30 or more days Some Heavy Pot Smokers have reported being positive 45-90 days after quitting On a Saliva Drug Test, THC will test positive within one hour of use, but may only show positive for about 12 hours after last use