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Regarding ischemic stroke, it has been suggested that bee venom toxins may cause hemolysis and endothelial damage, leading to the release of tissue thromboplastins and potentially promoting a state of disseminated intravascular coagulation (DIC), with blood vessel occlusion by fibrin thrombi (Figure 4) ( FIGURE 4 Despite the uncertainty regarding the mechanisms of stroke production, the management of these patients should include prompt recognition and collaboration with experienced physicians to ensure the administration of specialized treatments ( In todays world, as more people live on the edges of agricultural zones and in proximity to fields, bees and other stinging insects increasingly find themselves nesting in homes or buildings close to human activity