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Gilbert is credited with the creation of the first device that closely resembled the modern e-cigarette, receiving a patent in 1965

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The output of the device was recorded by a standard analogue-to-digital recording system (PowerLab 8/35, AD Instruments, Oxford UK), and physiological parameters (respiration via a respiratory belt around the subjects chest, and cardiac data via a pulse-oximeter on the index finger of the left hand) were recorded on the same system