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In a frequently cited study, GHK-Cu introduced by repeated injection into stainless-steel wire-mesh wound chambers implanted subcutaneously in rats produced a concentration-dependent increase in the accumulation of connective tissue, raising dry weight, DNA, total protein, collagen, and glycosaminoglycan content at the repair site, while an inactive control tripeptide did not

The combination diet treatment exerted a significant additive effect in preserving the ratio of GSH/GSSG when compared to either 2% creatine or 1% CoQ 10 diet treatment (Fig