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Together, these results suggested to us the possibility that NAC-induced roGFP2 oxidation is caused by sulfane sulfur (S 0 ) species created inside mitochondria, based on the following consideration (summarized in Figure 1E): It is known that H 2 S is very efficiently oxidized by sulfide:quinone oxidoreductase (SQR) to yield hydropersulfides inside the mitochondrial matrix (Libiad et al., 2014)

Beyond its role in collagen, vitamin C is a potent antioxidant that neutralizes free radicals and protects skin cells from oxidative damage

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Step 4: Post-Care Since the procedure has minimal downtime, patients can resume their routine immediately