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doi: 10.1016/0042-6822(89)90224-9 11 DeS.Chavez-CalvilloG.WahlstenM.MakkinenK

However, in people with T2D and MASLD, 24 weeks of efinopegdutide 10 mg reduced liver fat content by 72.7% compared to 42.3% reduction with semaglutide 1 mg despite similar WL achieved with both interventions [79]

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Although the number of Slc7a11 -expressing dendritic cells or fibroblasts within TLS is limited (Supplemental Figure 5) and the mechanism by which this small population contributes to the substantial glutathione accumulation within TLS (Figure 1) remains unclear, our findings suggest that Slc7a11 -expressing dendritic cells and fibroblasts play a pivotal role in driving glutathione synthesis within the microenvironment of TLS