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Role of metallothioneins 1 and 2 in ocular neovascularization

Supporting enzymes such as COMT (catechol-O-methyltransferase) helps convert catechol estrogens into safe forms

In patients receiving multiple transplants, and who are on cyclosporine, rifampicin cannot be used as it reduces the concentration of cyclosporine very substantially as a result of hepatic enzyme induction

Patients with chronic pancreatitis have lower levels of glutathione, cysteine, and glycine.[ref] Increasing cysteine levels with NAC is protective against pancreatic damage.[ref] Schizophrenia: Several research studies show that people with schizophrenia have lower glutathione levels in certain regions of the brain.[ref] In aging: The studies on glutathione in aging show that there is usually a general decrease in serum glutathione levels as we age